Altered Ion-responsive Gene Expression in Mmp20 Null Mice
نویسندگان
چکیده
منابع مشابه
Enamel proteins and proteases in Mmp20 and Klk4 null and double-null mice.
Matrix metalloproteinase 20 (MMP20) and kallikrein-related peptidase 4 (KLK4) are thought to be necessary to clear proteins from the enamel matrix of developing teeth. We characterized Mmp20 and Klk4 null mice to better understand their roles in matrix degradation and removal. Histological examination showed retained organic matrix in Mmp20, Klk4, and Mmp20/Klk4 double-null mouse enamel matrix,...
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Matrix metalloproteinase 20 (MMP20) and kallikrein-related peptidase 4 (KLK4) are secreted proteinases that are essential for proper dental enamel formation. We characterized and compared enamel formed in wild-type, Mmp20 (-/-), Klk4 (-/-), Mmp20 (+/-) Klk4 (+/-), and Mmp20 (-/-) Klk4 (-/-) mice using dissecting and light microscopy, backscattered scanning electron microscopy (bSEM), SEM, micro...
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ژورنال
عنوان ژورنال: Journal of Dental Research
سال: 2010
ISSN: 0022-0345,1544-0591
DOI: 10.1177/0022034510384625